Neuroimaging
The aim of our research is to describe the pathological process resulting from a known cause or injury that take place during the development of acquired epilepsy. We focus mainly on alterations in energy metabolism and cerebral perfusion. We strive for the ultimate translation of the acquired knowledge and its implementation into the clinical practice. We also focus on the improvements of epilepsy diagnostic imaging procedures, especially magnetic resonance imaging (MRI). In close collaboration with the Department of Radiology, Department of Neurology, and the Department of Paediatric Neurology, we have been validating for clinical practice the assessment of non-Gaussian diffusion (DKI), perfusion (DSC, pcASL) blood-brain barrier permeability (DCE, DEBBIE ASL), and newly electrical properties of tissue (MR-EPT). We also develop the post-processing methods and implement modern techniques, including artificial intelligence algorithms.
Research areas
Acquired epilepsy
In our group we try to describe the changes that take place during the development of so-called acquired epilepsy. I focus mainly on changes in energy metabolism and cerebral perfusion. We are trying to translate the knowledge that my colleagues and I are gaining into clinical practice. We focus on improving the diagnosis of epilepsy using imaging methods, especially magnetic resonance imaging. In close collaboration with the Imaging Methods Clinic, the Neurology Clinic, and the Department of Child Neurology, we are validating for clinical practice the assessment of non-Gaussian diffusion (DKI), perfusion (DSC, pcASL) blood-brain barrier permeability (DCE, DEBBIE ASL), and newly electrical properties of tissue (MR-EPT). We are developing post-processing methods and implementing modern techniques including artificial intelligence algorithms.
Selected publications
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Current grant projects
NU21-08-00228
Detection of changes in microstructure and structural connectivity of focal cortical dysplasias using diffusion kurtosis imaging.
NU21-02-00289
Neuroimaging in prediction of haemorrhagic complications after mechanical recanalization treatment of ischemic stroke.
NU23-08-00460 PediTuMRI
Advanced Magnetic Resonance Imaging of Paediatric Brain Tumors.
National Recovery Program – Excelles
COGNI (NPO cooperation).
CADASIL (CERICA clinical trial).
MedWaveImage (EU-Interreg)
Microwave imaging technology transfer to innovate the medical sector.
International cooperation
University of Liverpool
UMC Utrecht
HZDR Dresden
Amsterdam UMC
Fraunofer MEVIS
University of Oslo
GliMR
University of South Carolina
IKEM
Keywords
epilepsy, magnetic resonance imaging, diffusion, perfusion, energy metabolism