WE INNOVATE IN EPILEPSY TREATMENT

By joint research, discoveries and innovation we seek to open the gate to new effective methods of prevention, diagnostics and treatment of epilepsy and thus to fundamentally improve quality of life of the patients and their families.

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ABOUT PROJECT

The current exponential technological developments in combination with multidisciplinary synergies have brought unique opportunities for innovative knowledge in research of epilepsy and its treatment.

Modern research of epilepsy, improved quality of diagnostic methods, development of new medicines, their successful and fast transfer to clinical practice – all this requires close and efficient cooperation not only between experimental and clinical epileptologists but also with molecular biologists, mathematicians, bioengineers, biochemists, pharmacologists and many other specializations connected by the common research topic – epilepsy.

THE EPILEPSY RESEARCH CENTRE (EpiReC)

  • represents a unique platform in the Czech Republic that specializes in epilepsy and combines research with clinical practice

  • represents a unique platform in the Czech Republic that specializes in epilepsy and combines research with clinical practice

  • will have a strong internationally recognized research team

  • will identify new global directions in research and treatment of epilepsy

  • will use its outputs in clinical care of patients with epilepsy which will not only improve the care but also make it more efficient

  • will enable more efficient integration into international consortiums of leading epileptology workplaces that are primarily approached by pharmaceutical or technology companies to test new medicines or new treatment procedures

  • will be unique in terms of its multidisciplinary teams and translation medical research that will enable transfer of new knowledge from the molecular level

  • is planning contracted research focusing primarily on pre-clinical testing of new medicines and treatment procedures in experimental models of epilepsy and seizures and on clinical studies of unique groups of adult or children patients with epilepsy that are available to the centre

  • will create an innovative environment which will attract top scientific teams (primarily made up of young experts)

PARTNERS

The Institute of Physiology of CAS is a leading research institute dealing with research of normal and pathological physiology and it concentrates mainly on investigation of mechanisms of genesis of serious human diseases, e.g. vascular diseases and strokes, diabetes, inherited metabolic disorders and neurodegenerative diseases.

In the Centre the Institute will perform basic and pre-clinical research and processing and evaluation of data.

The Second Faculty of Medicine, Charles University ranks among the best medical faculties in the Czech Republic. Its priorities include internationally recognized medical research; the scientific potential of the faculty strongly relies on its postgraduate students.

In the Centre it will provide for basic, pre-clinical and clinical research.

The Motol University Hospital is an allowance organization directly managed by the Ministry of Health of the Czech Republic and it is one of the most prestigious medical institutions in the country. A broad range of its activities covers nearly all areas of medical care and in many fields also highly specialized services.

In the Centre the Hospital will provide for clinical research.

Faculty of Electrical Engineering, Czech Technical University in Prague educates specialists in electrical engineering, communication technology, automation, informatics and computer technology.

In the Centre it will provide for processing and evaluation of experimental and clinical data.

MANAGEMENT

The project´s management structure consists of a Management Committee, project management team and Scientific Board.

The Management Committee controls and monitors the purpose, vision, mission and proper economic management of the project. It has seven members representing all the project partners.

The management (project management team) is a project´s executive body. It consists of two members—the Project Manager and the Deputy Project Manager.

The Scientific Board provides particularly feedback relating to the scientific concept and submits recommendations for priority research topics. The Board has eight members.

Chairperson of the Management Committee

Prof. Vladimír Komárek, M.D.

The Second Faculty of Medicine, Charles University

Deputy Chairperson of the Management Committee

Assoc. Prof. Jakub Otáhal, M.D., Ph.D.

The Institute of Physiology of CAS

Member of the Management Committee

Prof. Roman Čmejla

Faculty of Electrical Engineering, Czech Technical University in Prague

Member of the Management Committee

Prof. Pavel Kršek, M.D., Ph.D.

The Motol University Hospital

Member of the Management Committee

Prof. Petr Marusič, M.D., Ph.D.

The Second Faculty of Medicine, Charles University

Member of the Management Committee

Jan Kopecký, M.D.

The Institute of Physiology of CAS

Member of the Management Committee

Jana Zárubová, M.D.

The Motol University Hospital

Project Manager

Prof. Přemysl Jiruška, M.D., Ph.D.

The Institute of Physiology of CAS

Deputy Project Manager

Assoc. Prof. Jakub Otáhal, M.D., Ph.D.

The Institute of Physiology of CAS

SCIENTIFIC BOARD

The Scientific Board is made up of internationally recognized experts in epileptological research and of scientific representatives of pharmaceutical companies

Marco de Curtis

Foundation of the Carlo Besta Neurological Institute, IRCCS, Milan, Italy

Helen Cross

University College London, Great Ormond Street Hospital for Children, London, United Kingdom

Stefanie Dedeurwaerdere

Union Chimique Belge (UCB Pharma), Brussels, Belgium

John Jefferys

Brasenose College, Departments of Pharmacology and Biochemistry University of Oxford, Oxford, United Kingdom

Michael Duchowny

Nicklaus Children’s Hospital, Department of Neurology, University of Miami School of Medicine, Miami, FL, USA

Merab Kokaia

Department of Clinical Sciences, Lund University, Lund, Sweden (TBC)

Jan Starý

Department of Paediatric Haematology and Oncology, Second Faculty of Medicine, Charles University and Motol University Hospital, Prague, Czech Republic

Hana Kubová

Department of Developmental Epileptology, Institute of Physiology, Czech Academy of Sciences, Prague, Czech Republic

CONTACT

Project Manager

Prof. Přemysl Jiruška, M.D., Ph.D.

premysl.jiruska@fgu.cas.cz

phone +420 241 062 739