Ondrej Novak, MSc, PhD

Team Leader

ondrej.novak@lfmotol.cuni.cz

Laboratory of Neural Circuit Optophysiology

Department of Physiology, Second Faculty of Medicine, Charles University

Scientific background

Head of the Laboratory of Neural Circuits Optophysiology at the Institute of Physiology, Second Faculty of Medicine, Charles University. Master’s degree in Physics. PhD in Neuroscience.

Research interests

Seizure genesis and propagation on single-cell and cell type-specific level; Correspondence of neural circuit malfunction and specific epilepsy hallmarks; Focal cortical dysplasia microenvironment; Causal epilepsy therapy; Glioblastoma theranostics; Building advanced optical setups

Selected publications

Chvojka J, Prochazkova N, Rehorova M, Kudlacek J, Kylarova S, Kralikova M, Buran P, Weissova R, Balastik M, Jefferys JGR, Novak O, and Jiruska P. Mouse model of focal cortical dysplasia type II generates a wide spectrum of high-frequency activities. Neurobiology of Disease 190: 10, 2024. https://doi.org/10.1016/j.nbd.2023.106383

Abdelfattah AS, Kawashima T, Singh A, Novak O, Liu H, Shuai YC, Huang YC, Campagnola L, Seeman SC, Yu JN, Zheng JH, Grimm JB, Patel R, Friedrich J, Mensh BD, Paninski L, Macklin JJ, Murphy GJ, Podgorski K, Lin BJ, Chen TW, Turner GC, Liu Z, Koyama M, Svoboda K, Ahrens MB, Lavis LD, and Schreiter ER. Bright and photostable chemigenetic indicators for extended in vivo voltage imaging. Science 365: 699-+, 2019. https://doi.org/10.1126/science.aav6416

Kazemipour A, Novak O, Flickinger D, Marvin JS, Abdelfattah AS, King J, Borden PM, Kim JJ, Al-Abdullatif SH, Deal PE, Miller EW, Schreiter ER, Druckmann S, Svoboda K, Looger LL, and Podgorski K. Kilohertz frame-rate two-photon tomography. Nature Methods 16: 778-+, 2019. https://doi.org/10.1038/s41592-019-0493-9