Pavla Hosenseidlova, Bc
Student
Laboratory of Neuroglial Interactions
Department of Physiology, Second Faculty of Medicine, Charles University
Scientific background
I completed a Bachelor’s degree in General Biology at the Faculty of Science, Charles University, during which I undertook a professional internship at the Department of Physiology at Charles University. There, I focused on working with cell cultures and became familiar with fundamental techniques such as electrophoresis and western blot, which I applied in studying protein expression and sample analysis. Throughout my studies, I gained theoretical knowledge in various biological and biochemical methods, along with a deeper understanding of multiple branches of biology, including neuroscience.
Currently, I am pursuing a Master’s degree, again at the Faculty of Science, Charles University, specializing in Animal and Human Physiology with a focus on Neurobiology. As part of my studies, I am working on a thesis that explores the effects of neurosteroids on epilepsy using the patch clamp technique.
Research interests
My research interests focus on neurophysiology and pharmacology, specifically on the mechanisms underlying neurological and psychiatric disorders and potential therapeutic approaches. In my Bachelor’s thesis, I explored opioid addiction, concentrating on understanding withdrawal syndrome and its treatment options. This experience deepened my interest in substances affecting the central nervous system, and I became particularly drawn to topics related to the use of psychedelics in psychiatry and their effects on neuroplasticity and the treatment of mental disorders.
Currently, in my Master’s program in neurophysiology, I am focusing my research on epilepsy, investigating the effects of neurosteroids on epileptic processes using the patch clamp electrophysiology method. This project allows me to understand how neurosteroids can influence ion channels and neuronal excitability, which could potentially lead to the development of more targeted therapies.
In the future, I would like to focus on research in neurodegenerative and psychiatric diseases, with the aim of contributing to the development of innovative and more effective treatment methods.
Selected publications
—
More information
—