Mgr. Ondřej Novák, Ph.D.

ondrej.novak@lfmotol.cuni.cz

Ústav fyziologie, 2. LF UK

NeuroImaging

Team leader

Head of the Laboratory of Naural Circuits Optophysiology at the Institute of Physiology, Second Faculty of Medicine, Charles University. Master’s degree in Physics. PhD in Neuroscience.

Research interests

Seizure genesis and propagation on single-cell and cell type-specific level; Correspondence of neural circuit malfunction and specific epilepsy hallmarks; Focal cortical dysplasia microenvironment; Causal epilepsy therapy; Glioblastoma theranostics; Building advanced optical setups

The most important publications

Chvojka J, Prochazkova N, Rehorova M, Kudlacek J, Kylarova S, Kralikova M, Buran P, Weissova R, Balastik M, Jefferys JGR, Novak O, and Jiruska P. Mouse model of focal cortical dysplasia type II generates a wide spectrum of high-frequency activities. Neurobiology of Disease 190: 10, 2024.

Abdelfattah AS, Kawashima T, Singh A, Novak O, Liu H, Shuai YC, Huang YC, Campagnola L, Seeman SC, Yu JN, Zheng JH, Grimm JB, Patel R, Friedrich J, Mensh BD, Paninski L, Macklin JJ, Murphy GJ, Podgorski K, Lin BJ, Chen TW, Turner GC, Liu Z, Koyama M, Svoboda K, Ahrens MB, Lavis LD, and Schreiter ER. Bright and photostable chemigenetic indicators for extended in vivo voltage imaging. Science 365: 699-+, 2019.

Kazemipour A, Novak O, Flickinger D, Marvin JS, Abdelfattah AS, King J, Borden PM, Kim JJ, Al-Abdullatif SH, Deal PE, Miller EW, Schreiter ER, Druckmann S, Svoboda K, Looger LL, and Podgorski K. Kilohertz frame-rate two-photon tomography. Nature Methods 16: 778-+, 2019.

Researcher ID

0000-0002-8874-4252